Lymphatic muscle cells (LMCs) are indispensable for lymphatic vessel contraction, and their aberrant recruitment or absence is associated with both primary and secondary lymphedema. Despite their ...

This manuscript by Kaur et al. identifies differential gene expression in distinct cell populations, specifically myeloid and lymphoid cells, following short-term exposure to e-cigarette aerosols with ...

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

Wild-type and Il1b-deficient mice on a C57BL/6 background were subjected to chronic HDM exposure over a 5-week period, and scRNA-seq was performed to characterize changes in the lung immune landscape.

Abstract: Single-cell RNA sequencing (scRNA-seq) has profoundly reshaped our understanding of cellular diversity and functionality; however, accurate cell-type annotation is required for biological ...

If you're serving hard time inside a California prison, you'll often find yourself stuck in a cramped cell with a complete stranger. You hang a bedsheet to manufacture the semblance of privacy between ...

Background: Lung tissue exhibits intricate spatial organization and dynamic cellular interactions. However, the molecular mechanisms underlying pulmonary arterial hypertension (PAH) remain poorly ...

Background Most patients with biliary tract cancer (BTC) do not derive durable clinical benefit (DCB) from immune checkpoint inhibitors (ICIs), underscoring the urgent need for predictive biomarkers.

Acute rejection is a significant cause of impaired graft survival in the early post-transplantation period, and the early-stage immune cell dynamics with local intercellular communication during this ...

Y. Liu et al., Data from “Single-cell transcriptomics reveals the complexity of the tumor microenvironment of treatment-naive osteosarcoma.” Gene Expression ...

The liver is remarkable for its ability to regenerate after injury, yet when this process fails, acute liver failure (ALF) carries devastating outcomes. Traditional research methods, reliant on bulk ...