The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins -- yet it exists in large quantities. A research team has ...
A new study published in the journal Cell shows that a non-coding RNA molecule regulates mitochondrial gene expression in human cells. The work results from a collaboration between the University of ...
Long non-coding RNAs (lncRNAs) are RNA transcripts longer than 200 nucleotides that do not code for proteins. Once considered ...
本研究针对精神分裂症(SCZ)中非编码RNA(ncRNA)协同作用机制不明的科学问题,揭示了miR-137通过调控SCZ相关转录因子网络增强lncRNA GOMAFU表达的新通路。研究人员发现组蛋白乙酰化通过诱导miR-137靶标E2F6等转录抑制因子下调GOMAFU,而miR-137通过整合表观遗传和转录调控 ...
The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins – yet it exists in large quantities. A research team from ...
An important player in the healthy development of female embryos turns out also to play a key role in regulating the behavior of chromosome loops and gene expression in both sexes, according to a new ...
Although evolution awarded us with appendages and complex sensory systems, the human body, much like a worm, is simply a large tube transporting food from one end to the other. It is hard to imagine ...
酒精暴露小鼠经吗啡治疗后出现痛觉过敏,脊髓转录组学分析揭示非编码RNA失调(如circPan3、lncSnhg14上调,circNr3c2、circAnkrd12下调),涉及炎症反应和氧化应激,为FASD相关慢性疼痛提供新机制。 这项研究聚焦于孕期酒精暴露(Prenatal Alcohol Exposure, PAE)与阿片类 ...
Cancer is most treatable in its early stages, so finding innovative and non-invasive methods to diagnose cancer early on is crucial for fighting the disease. Liquid biopsies, which require just a ...
Two types of RNA in our cell: Coding RNA directs cells to make proteins; Non-coding RNA performs a wide range of activities including gene regulation and maintaining chromosome structure. Please ...
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