Autophagy is a highly regulated intracellular process to maintain cellular homeostasis by degrading damaged proteins and organelles. Dysregulation of autophagic activity in cardiomyocytes is ...

In a two-color experiment (panel a in the figure) DNA from individuals of the same species or different tissue from a single individual (e.g., normal and diseased cells) is extracted and ...

High-throughput tissue microarray allows many clinical specimens to be analyzed simultaneously on a single slide. One potential limitation of tissue microarray is the correct representation of each ...

The widespread use of mobile phones has led to public concerns about the health effects associated with exposure to radiofrequency (RF) fields. The paramount concern of most persons relates to the ...

A survey of scientists developing bioprocesses found efficiency to be the top concern, with pressure growing each year to “produce more, do it more quickly, and do so with fewer resources.” 1 Yet, ...

Spotfire, Inc. has announced DecisionSite® for Microarray Analysis (DSMA), which gives drug makers a competitive advantage in quickly and accurately identifying potential drug targets. DSMA, available ...

Expression noise is inherent to microarray-based measurement of gene expression. Noise can be defined as gene expression variation that does not correlate with the biology or behavior being studied ...

Protein and peptide microarrays, the emerging tools for proteomics and clinical assays, are high-throughput methods that track binding events and activities, and decide the function of proteins on a ...

Microarrays provide a way of organizing biological samples for high-throughput analysis. Samples are arranged in columns and rows upon a support surface consisting of a glass slide, a nitrocellulose ...

Activation of and dependence on ataxia telangiectasia mutated kinase in PTEN-deficient tumor cells. Topoisomerase II alpha gene status, HER2, and microtubule-associated protein tau as predictors of ...

Schott has launched the next generation of microarray slides: Nexterion ® HiSens. These slides are designed to increase the signal to noise ratios of microarray experiments by over eight times and ...

A new palm-sized microarray that holds 1,200 individual cultures of fungi or bacteria could enable faster, more efficient drug discovery, according to a study published in mBio®, the online ...