The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

Before the development of efficient single-cell technologies such as single-cell RNA sequencing, researchers studied genes, gene expression and proteins in bulk. These methods report the molecular ...

In a recent perspective article published in the journal Nature Communications, over 30 scientists from around the world discussed the action plans and principles of the global scientific initiative ...

An initiative partly funded by the Wellcome Trust Sanger Institute in the UK has moved further towards its goal of producing a 'human cell atlas' (HCA) to map every cell type in the human body.

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Dr. Xuyu Qian in his current laboratory, standing beside a collection of external hard drives containing raw spatial transcriptomics data from his groundbreaking human brain development research. The ...

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

Technological development is key to improving the way hematologic cancer is diagnosed and treated. With this vision, the Josep Carreras Leukemia Research Institute is committed to the creation and ...