Research is shaking up how we think about evolution, suggesting there's a level of predictability influenced by genes and genetic history.

A Mendelian randomization study reveals PCSK9 inhibitors may reduce low back pain (LBP) risk, while HMGCR and NPC1L1 inhibitors show no significant association, providing genetic evidence for ...

This study explores the relationship between gallstones, cholecystectomy, and cancer risk through both observational and Mendelian randomization (MR) methods. The research aims to clarify the ...

A Multicenter Open-Label Randomized Phase II Study of Osimertinib With and Without Ramucirumab in Tyrosine Kinase Inhibitor–Naïve EGFR-Mutant Metastatic Non–Small Cell Lung Cancer (RAMOSE trial) The ...

Pharmacogenetic testing, which is used to classify how patients with major depressive disorder (MDD) metabolize medications, reduces adverse drug-gene interactions, new research shows. In a randomized ...

Mezigdomide (a CELMoD) combined with carfilzomib/dexamethasone met the phase 3 primary endpoint, delivering statistically ...

The same BMI criteria were used to determine eligibility for study randomization. Any individual who completed the run-in phase but did not fulfill the BMI randomization criteria was considered ...

Radiographic Progression-Free Survival and Clinical Progression-Free Survival as Potential Surrogates for Overall Survival in Men With Metastatic Hormone-Sensitive Prostate Cancer Patients with ...

Quadrivalent recombinant influenza vaccines contain three times the amount of hemagglutinin protein as standard-dose egg-based vaccines, and the recombinant formulation is not susceptible to antigenic ...