A metabolic enzyme studied for over seven decades has a hidden second function—it can unwind RNA and promote cell cycle progression, an additional function beyond its role in energy production, ...

Researchers engineered the first RNA-based NAND gate in living cells using deep learning and Bayesian optimization, testing ...

An interdisciplinary research team from two working groups at the Center for Synthetic Biology at TU Darmstadt has developed ...

CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing attention as a next-generation gene therapy platform due to its precision and reduced side effects. Utilizing this system, ...

Contrary to historic understanding of RNA’s longevity in cells, some RNAs can persist in cells throughout the life of an organism. Lead authors, Martin Hetzer, PhD, president of the Institute of ...

A new sequencing-based method uses molecular barcodes to trace synaptic connections among neurons. The approach enables large ...

This work presents a redox-responsive strategy for precise RNA control via post-synthetic 2′-OH acylation. These introduced disulfide-containing acyl groups can be selectively cleaved upon exposure to ...

RNA in cells performs an astounding number of functions. Messenger RNA carries the sequences of active genes to cellular machinery that turns it into proteins. And transfer RNA molecules are an ...

A study of a bacteria commonly used in dairy fermentation revealed how organized RNA helixes, called riboswitches, can combine different signals to keep gene expression in check. Researchers from the ...

Nanoparticles that deliver self-amplifying RNA were found to reduce scarring and improve heart function in animals following ...