Aligning cancer quality metrics across the continuum of community-based and academic medicine using a prioritization tool. This is an ASCO Meeting Abstract from the 2012 Quality Care Symposium. This ...

The Pig-A gene plays a pivotal role in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors, which tether a multitude of proteins to the cell surface. Mutations in this X‐linked gene result ...

Cancer is essentially a genetic disease, in that alterations to DNA, including mutations, amplifications, deletions, and translocations, change a gene’s normal function to promote growth, survival, ...

The illustration of protein structure (domains) on the left side, and corresponding exons in the FLT3 gene are displayed on the right side. FMS-like tyrosine kinase 3 (FLT3) mutations represent some ...

Previously, it was recommended for women who have a family history of breast, ovarian, tubal or peritoneal cancer to be assessed for harmful BRCA1 or BRCA2 mutations. That recommendation was last made ...

To ensure it complies with the CE marking, the DNA is first isolated from a specimen of formalin-fixed paraffin-embedded tissue using the QIAamp DNA FFPE Tissue Kit. The total amount of DNA in the ...

“However, such existing testing tools and mutation testing approaches may be inefficient and/or impractical for some types of programming languages. For example, source code for a software application ...

In May 2013, nearly 20 years after the discovery that mutations on the BRCA1 and BRCA2 genes could lead to a higher risk of breast and ovarian cancer, A-list Hollywood actress Angelina Jolie garnered ...