Transrectal ultrasonography and prostate biopsy are important office procedures for urologists. Indeed, since the introduction of PSA screening and with active surveillance becoming more widespread, ...

Dr. Johnny Mao first learned that facial plastic surgery using local anesthesia was possible by doing facial reconstruction ...

Local anesthetics have transformed clinical practice by enabling a broad range of minor and major procedures with minimal discomfort. Although adverse reactions are frequently reported, genuine ...

Is local infiltration of an abdominal wound with an anesthetic as effective as epidural anesthesia for the control of postoperative pain? The authors of this article combined the results of 9 ...

The localized loss of sensation with resultant reduction in pain stimuli is the end result of local anesthesia. This mode of anesthesia is considered to be safer than general anesthesia, because it ...

The latest procedure gaining attention is “awake-only” liposuction, often marketed as a safer, faster alternative to ...

Medical researchers bringing surgical patients closer to having a long-acting local anesthetic. In a randomized, double-blind trial, patients given neosaxitoxin, a new local anesthetic derived from ...

The choice of needle diameter can influence the pain felt by the patient. A well-designed randomized controlled trial (RCT) showed an inverse relation between needle diameter and pain.1 A smaller ...

A topical mucoadhesive tablet containing the antidepressant amitriptyline significantly reduced pain from needle pricks in a small, randomized controlled clinical trial. The researchers said the ...

What's the maximum recommended dose for lidocaine or mepivacaine during dental procedures? The answer remains unclear as guidelines published by dental organizations differ from those of manufacturers ...

Research posted to the bioRxiv* preprint server has shown that procaine and procaine-hydrochloride can reduce replication of SARS-CoV-2 and influenza A viruses in infected cells and reduce the ...