Before the development of efficient single-cell technologies such as single-cell RNA sequencing, researchers studied genes, gene expression and proteins in bulk. These methods report the molecular ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

An initiative partly funded by the Wellcome Trust Sanger Institute in the UK has moved further towards its goal of producing a 'human cell atlas' (HCA) to map every cell type in the human body.

Dr. Xuyu Qian in his current laboratory, standing beside a collection of external hard drives containing raw spatial transcriptomics data from his groundbreaking human brain development research. The ...

In a recent perspective article published in the journal Nature Communications, over 30 scientists from around the world discussed the action plans and principles of the global scientific initiative ...

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

Spatial biology is reshaping how researchers study cancer by revealing the architecture and complexity of tumors in extraordinary detail. Through techniques that combine protein- and gene-level ...

Complete Genomics will share details of various multi-omics and spatial transcriptomics applications based on its sequencing technology at the 2024 American Society of Human Genetics (ASHG) Meeting.

Technological development is key to improving the way hematologic cancer is diagnosed and treated. With this vision, the Josep Carreras Leukemia Research Institute is committed to the creation and ...

This eBook cuts through the complexity of spatial techniques, featuring a series of interviews with pioneers in the field, and peer-reviewed research from the Taylor & Francis journal portfolio. This ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...