Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years. Though ...

Researchers create a massive single-cell atlas of the aging mouse brain, revealing how epigenetic changes and "jumping genes" drive neurodegeneration.

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to ...

Before the development of efficient single-cell technologies such as single-cell RNA sequencing, researchers studied genes, gene expression and proteins in bulk. These methods report the molecular ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

In a recent perspective article published in the journal Nature Communications, over 30 scientists from around the world discussed the action plans and principles of the global scientific initiative ...

Complete Genomics will share details of various multi-omics and spatial transcriptomics applications based on its sequencing technology at the 2024 American Society of Human Genetics (ASHG) Meeting.

An initiative partly funded by the Wellcome Trust Sanger Institute in the UK has moved further towards its goal of producing a 'human cell atlas' (HCA) to map every cell type in the human body.

An international team of scientists and clinicians has announced the launch of a new open-access 3D portal that allows users to explore intact human organs in unprecedented detail—from the whole organ ...

A team led by HHMI Hanna Gray Fellow Shan Meltzer has created a detailed, cell-by-cell map of the spinal cord that offers a new framework for understanding chronic pain and provides a powerful new ...