Ubiquitin is a small protein consisting of 76 amino acids that binds to lysine residues of substrates, usually by a combination of three enzymes: a ubiquitin-activating enzyme (E1, two types), a ...

Specific glycans attached to the GnT-IVa and GnT-IVb can bind to the enzyme’s ligand-binding site, interfering with recognition and binding to the glycosylation proteins’ normal glycoprotein ...

Glycans are important complex carbohydrates found on cell surfaces that serve crucial roles in cell-to-cell communication, structure, and protection. They are attached to many proteins in the body, ...

Glycans are important complex carbohydrates found on cell surfaces that serve crucial roles in cell-to-cell communication, structure, and protection. They are attached to many proteins in the body, ...

The Metabolic Disease Laboratory provides services for the diagnosis of lysosomal storage diseases. The laboratory provides screening of urine for glycosaminoglycans, oligosaccharides, sialic acid, ...