Animal breeding has traditionally focused on improving mean trait performance; however, contemporary research increasingly highlights the significance of genetic variation not only in trait means but ...

Clinicians' ability to diagnose and treat chronic diseases is limited by scientific uncertainty around factors contributing to disease risk. A study published September 2 nd in the open-access journal ...

Study has combined genome-wide data with plasma proteomics from a Ugandan cohort to map hundreds of genetic regulators of ...

The past decade has delivered landmark advances in human and medical genomics that shape how we understand disease mechanisms ...

The human genome is organised in 46 chromosomes, where all but the x and y chromosomes in men are present in two copies. This means that a person with a faulty gene on one chromosome most often has a ...

Detecting genetic variants associated with the variance of complex traits, that is, variance quantitative trait loci (vQTLs), can provide crucial insights into the interplay between genes and ...

Researchers have significantly expanded the catalogue of known human genetic variation. The resulting datasets, shared in two back-to-back publications in the journal Nature, constitute what may be ...

The COVID-19 pandemic gave us tremendous perspective on how wildly symptoms and outcomes can vary between patients ...

Knowing how human DNA changes over generations is essential to estimating genetic disease risks and understanding how we evolved. But some of the most changeable regions of our DNA have been ...

Genetic inheritance may sound straightforward: One gene causes one trait or a specific illness. When doctors use genetics, it’s usually to try to identify a disease-causing gene to help guide ...