The design of a two-color microarray experiment can be considered as having three layers. Figure 1 shows an example of an experiment that compares the effects of two treatments—A and B—on ...

Amid growing concerns about the poor design of animal experiments and its implications for the translatability of experimental results, Michael F. W. Festing thinks it's time we do something about it.

Preclinical model systems are invaluable tools for drug discovery and development. But many complex diseases, such as nonalcoholic steatohepatitis (NASH), are difficult to recapitulate in the ...