Microtubules are dynamic, tubular polymers composed of αβ-tubulin dimers that form an essential framework within eukaryotic cells. They orchestrate a wide range of cellular functions including ...

After three years of study, the researchers found that alpha-synuclein, a protein closely linked to Parkinson’s disease, forms an abnormal connection with an enzyme called ClpP. This enzyme normally ...

Researchers at the Icahn School of Medicine at Mount Sinai have characterized how cellular senescence—a biological process in ...

BAP31 is a ubiquitously expressed transmembrane protein predominantly localised within the endoplasmic reticulum (ER), where it functions as a molecular chaperone and sorting factor. It plays a ...

WUHAN, Jan. 25 (Xinhua) -- A collaborative team of Chinese and U.S. scientists has identified a specific group of highly adaptable tumor cells that act as a central hub driving lung cancer progression ...

Single-cell analysis is a ubiquitous laboratory technique that allows researchers to probe the myriad biomolecular states of cells. Single-cell assays can reveal gene and protein expression patterns, ...

In the rapidly evolving field of drug discovery, single-cell analysis has become an invaluable tool for understanding cellular heterogeneity and molecular pathways. However, traditional single-cell ...

Siegfried Musser and his team in the Department of Cell Biology and Genetics at the Texas A&M College of Medicine used an advanced imaging technique called MINFLUX to track molecular movements in ...

Microtubules perform an active role in communication within the cell by transmitting received signals to the cell's functional units. Researchers at the Paul Scherrer Institute PSI and the Department ...

Short-term IF boosts glucose homeostasis, but prolonged fasting in adolescence may impair β cell maturation—potentially linking chronic IF to type 1 diabetes risk. Study: Chronic intermittent fasting ...

Researchers identified DMTF1 as a key transcription factor driving neural stem cell regeneration during aging. The study ...

A new study reveals that age-related changes in the gut microbiota directly impair intestinal stem cell (ISC) function and that restoring a youthful microbial environment can reverse this decline.