In this article, the authors demonstrate that a normal-phase chromatographic method was stability-indicating for a water-sensitive prodrug. The stress conditions using aqueous and non-aqueous ...

Development of a selective and fast LC-MS/MS for determination of WSJ-537, an xanthine oxidase inhibitor, in rat plasma: Application to a pharmacokinetic study. Development of two step liquid-liquid ...

Chromatography of charged analytes is often challenging as they are not retained effectively on the commonly used reversed phase columns and elute in the dead volume. On columns with polar or aqueous ...

When the components in the mixture of solutions are moved forward in the mobile phase by the material moving the sample, these components pass through the stationary phase. The difference in size and ...