Antibiotics are among the most frequently prescribed drugs in medicine. Their use, however, is often limited by associated renal toxic effects. The most common manifestation of these toxic effects is ...

Paracrine communication between different parts of the renal tubule is required for the maintenance of systemic acid–base balance, say researchers. “We demonstrate that the kidney regulates acid–base ...

To the Editor: In the June 20 issue of the Journal, Schwartz and Relman present an article on acid–base disorders in which they criticize some newer parameters used in their evaluation. A criticism by ...

The article by Berend et al. 1 in this issue of the Journal is the first in a series of review articles that consider approaches to the understanding and management of fluid, electrolyte, and ...

Describes acid-base physiology and discusses the diagnosis and treatment of disorders associated with metabolic acidosis and metabolic alkalosis, as well as plasma potassium disorders. Metabolic ...

(HealthDay News) — Electrolyte disturbances and acid-base disorders are common occurrences in patients with chronic alcohol-use disorder regardless of social circumstances, according to a review ...

A new study of patients receiving care for acute heart failure at Rambam Health Care Campus in Haifa, Israel, investigated how their clinical outcomes might be affected by elevated lactate levels and ...

COOH) represents the protonated form of the organic acid, whereas lactate (CH₃CH (OH)COO⁻) represents its conjugated base.